UT Southwestern researchers discovers clues as to why reflux can turn cells cancerous

Filed under: Esophageal Cancer

Researchers at UT Southwestern Medical Center and Dallas Veterans Affairs Medical Center report that society with acid reflux disease, particularly those with Barrett’s esophagus, have changed cells in their esophagus containing shortened telomeres. Telomeres are the ending sequences in DNA. that report along with other studies suggests that these shortened telomeres might allow cells more prone to cancer to take hold.

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HPV vaccines cannot treat women who are already infected

Filed under: Cervical Cancer

A new suggests that cervical cancer vaccines for human papillomavirus (HPV) do not reduce or eliminate preexisting infections.

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Test may catch ovarian cancer in early stages

Filed under: Ovarian Cancer, Research, Young Adult Cancers, Cancer Pre-vivors

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What’s in your water?

Filed under: Bladder Cancer, Prevention, Environment

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The Role of Combined Radiation and Chemotherapy in the Treatment of Esophageal Cancer

Esophageal cancer, including cancer arising from the gastro-esophageal junction, is a challenging disease worldwide. At diagnosis, approximately 50% of patients present with disease that extends beyond the site of origin in the esophagus(1). Patients who are not medically fit for surgery or who have disease that cannot be completely removed by surgery will need aggressive treatment with a combination of chemotherapy and radiation therapy. In patients with esophageal cancer that can be completely removed with surgery, the use of chemotherapy and radiotherapy before or after surgery may be needed to achieve a cure. Treatment with chemotherapy alone or chemotherapy plus radiotherapy are strategies that continue to be explored in investigational clinical trials. With improvement in surgical techniques and the use of multi-modality therapy, the overall five-year survival of esophageal cancer has improved from 4% in the 1970s to 14% today(2). New treatment strategies include identification of and directed treatment at specific molecular targets that are involved in the growth or spread of esophageal cancer cells. This article will highlight the role of combined chemotherapy and radiation therapy in the treatment of esophageal cancer with an emphasis on results from randomized, controlled clinical trials.

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NEW MESOTHELIOMA TREATMENT APPROACHES

New approaches to treat malignant mesothelioma are currently being tested. They often combine traditional treatments or include something entirely new. They include:

Angiogenesis and Anti-angiogenesis Drugs

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Survivor Spotlight: Renee, living life to the fullest

Filed under: Thyroid Cancer, Survivor Spotlight

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Fertility may be preserved after ovarian cancer

Filed under: Ovarian Cancer

Women with malignant ovarian germ cell tumors who undergo surgery intended to preserve fertility, in addition to platinum-based chemotherapy, are likely to maintain fertility, says a new study from MD Anderson Cancer Center in Houston. Malignant ovarian germ cell tumors occur in the eggs of the ovary and tend to affect young women.

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Alcohol increases cancer risks

Filed under: Breast Cancer, Bladder Cancer, All Cancers, Liver Cancer, Esophageal Cancer

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ABCs Robin Roberts’ doctor takes your questions

Filed under: Breast Cancer, Television, Celebrity news

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