Recent Posts
- Drug shows promise in prostate cancer spread to bone
- Ray of hope for human Usher syndrome patients
- Barrow researchers successfully destroy brain tumor cells
- Novel antibodies for combating Alzheimer’s and Parkinson’s disease
- Common diabetes drug may help treat ovarian cancer
- Origin of intelligence and mental illness linked to ancient genetic accident
- Molecular knock-out alleviates Alzheimer’s symptoms in mice
- Promising drug slows down advance of Parkinson’s disease and improves symptoms
Ray of hope for human Usher syndrome patients
After years of basic research, scientists at Johannes Gutenberg University Mainz (JGU) are increasingly able to understand the mechanisms underlying the human Usher syndrome and are coming ever closer to finding a successful treatment approach. The scientists in the Usher research group of Professor Dr. Uwe Wolfrum are evaluating two different strategies. These involve either the repair of mutated genes or the deactivation of the genetic defects using agents. Based on results obtained to date, both options seem promising. Usher syndrome is a congenital disorder that causes the loss of both hearing and vision.
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Drug shows promise in prostate cancer spread to bone
A new drug demonstrated dramatic and rapid effects on prostate cancer that had spread to the bone, according to a study reported by University of Michigan Comprehensive Cancer Center researchers.
About two-thirds of patients treated with cabozantinib had improvements on their bone scans, with 12 percent seeing complete resolution of uptake on bone scan. Bone scans assess the degree to which cancer is in the bone; improvements on these scans suggest a response to the drug.
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Barrow researchers successfully destroy brain tumor cells
A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph’s Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy. The study, “The Ketogenic Diet Is an Effective Adjuvant to Radiation Therapy for the Treatment of Malignant Glioma,” was published in PLOS ONE
Led by Adrienne C. Scheck, PhD, Principal Investigator in Neuro-Oncology and Neurosurgery Research at Barrow, the groundbreaking research studied the effects of the ketogenic diet in conjunction with radiation therapy for the treatment of malignant gliomas, an aggressive and deadly type of brain tumor. The ketogenic diet is a high-fat, low-carbohydrate diet that alters metabolism and is used in the treatment of pediatric epilepsy that does not respond to conventional therapies. The diet’s affects on brain homeostasis have potential for the treatment of other neurological diseases, as well.
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Common diabetes drug may help treat ovarian cancer
A new study suggests that the common diabetes medication metformin may be considered for use in the prevention or treatment of ovarian cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study found that ovarian cancer patients who took the drug tended to live longer than patients who did not take it.
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Novel antibodies for combating Alzheimer’s and Parkinson’s disease
Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer’s disease and Parkinson’s disease, as well as Type 2 diabetes, according to a new study.
The onset of these devastating diseases is associated with the inappropriate clumping of proteins into particles that are harmful to cells in the brain (Alzheimer’s disease and Parkinson’s disease) and pancreas (Type 2 diabetes). Antibodies, which are commonly used by the immune system to target foreign invaders such as bacteria and viruses, are promising weapons for preventing the formation of toxic protein particles. A limitation of conventional antibodies, however, is that high concentrations are required to completely inhibit the formation of toxic protein particles in Alzheimer’s, Parkinson’s, and other disorders.
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Origin of intelligence and mental illness linked to ancient genetic accident
Scientists have discovered for the first time how humans ? and other mammals ? have evolved to have intelligence.
Researchers have identified the moment in history when the genes that enabled us to think and reason evolved.
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Cancer Treatment
Drug shows promise in prostate cancer spread to boneA new drug demonstrated dramatic and rapid effects on prostate cancer that had spread to the bone, according to a study reported by...
Common diabetes drug may help treat ovarian cancerA new study suggests that the common diabetes medication metformin may be considered for use in the prevention or treatment...
Researchers report first success of targeted therapy in most common non-small cell lung cancerA new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that...
Possible new treatment for Ewing sarcomaDiscovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously...
Stem Cell Research
The potential impact of olfactory stem cells as therapy reported in Cell TransplantationA study characterizing the multipotency and transplantation value of olfactory stem cells, as well as the ease in obtaining them, has...
New stem cell technique promises abundance of key heart cellsCardiomyocytes, the workhorse cells that make up the beating heart, can now be made cheaply and abundantly in the laboratory. Writing...
From stem cell to brain cell – new technique mimics the brainA new technique that converts stem cells into brain cells has been developed by researchers at Lund University. The method is simpler,...
Stem-cell-growing surface enables bone repair—University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem...
Diabetes
Recovering ‘bodyguard’ cells in pancreas may restore insulin production in diabeticsThe key to restoring production of insulin in type I diabetic patients, previously known as juvenile diabetes, may be in recovering...
Breakthrough for new diabetes treatmentIn experiments on mice and rats, the scientists have managed to both prevent the development of type II diabetes and reverse...
Stop diabetes with insulin tabletsType 1 diabetes is the autoimmune form of diabetes, in which the patients’ insulin-producing beta cells are destroyed...
Sensor detects glucose in saliva and tears for diabetes testingResearchers have created a new type of biosensor that can detect minute concentrations of glucose in saliva, tears and urine...
Heart Disease
Umbilical cord cells outperform bone marrow cells in repairing damaged heartsA study published this month by researchers at the University of Toronto and Toronto’s Princess Margaret Hospital has...
Softening arteries, protecting the heartArterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple...
Major genetic discovery explains 10 percent of aortic valve diseaseResearchers at the Sainte-Justine University Hospital Center and University of Montreal have identified genetic origins in 10%...
Research yields two ‘firsts’ regarding protein crucial to human cardiac functionFlorida State University researchers led by physics doctoral student Campion Loong have achieved significant benchmarks in a study...