QBI neuroscientists make Alzheimer’s disease advance

Queensland Brain Institute (QBI) neuroscientists at UQ have discovered a new way to reduce neuronal loss in the brain of a person with Alzheimer’s disease.

Memory loss in people with Alzheimer’s disease can be attributed to several factors.

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Alzheimer’s Drug Research: What if the major drug companies are betting on the wrong horse?

– Alternative Theories Focus on Oxidative Stress
as Promising Avenue –

The major drug companies have spent hundreds of millions of dollars to develop an Alzheimers drug based largely on theory and hope as one scientist put it in a recent article in Forbes.

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Yale researchers clear up Alzheimer’s plaques in mice

Blocking a common immune system response cleared up plaques associated with Alzheimers Disease and enabled treated mice to recover some lost memory, Yale University researchers report Friday in the journal Nature Medicine.

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Model shows how mutation tips biochemistry to cause Alzheimer’s

Your fate can be determined by tiny events. Imagine you live in the city and you walk everywhere to get exercise you are healthy and not afraid of getting mugged. You almost never eat breakfast so you dont stop at the donut shop on the way to work, until one day the manager replaces the girl at the counter with her pretty red-haired younger sister. This seemingly unimportant change in your world is just enough to overcome your ability to resist high-fat temptation. A million donuts later, your cholesterol level surges and then your heart gives out. Curse you, little red-haired girl!

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Hopkins researchers discover new link to schizophrenia

Mouse model mimics clinical features

Neuroscientists at Johns Hopkins have discovered that mice lacking an enzyme that contributes to Alzheimer disease exhibit a number of schizophrenia-like behaviors. The finding raises the possibility that this enzyme may participate in the development of schizophrenia and related psychiatric disorders and therefore may provide a new target for developing therapies.

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New target for Alzheimer’s disease identified

Modulating enkephalin may reduce cognitive deficits

Alzheimers disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed.

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Investigators unveil new drug discovery tool for Alzheimer’s disease

An article published in the April issue of the Journal of Alzheimers Disease presents a detailed characterization of a new drug discovery tool for Alzheimer’s disease. It demonstrates that an abnormal form of tau protein, as it occurs in Alzheimer’s disease, can be produced in very simple cell models in an unambiguous way. Most importantly, it also shows an example of a chemical compound, found in nature, which is highly effective to completely suppress the abnormal changes of tau.

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Researchers close in on origins of main ingredient of Alzheimer’s plaques

The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer’s brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned.

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First diagnostic test for Alzheimer’s and Parkinson’s disease on the horizon

A new blood test that can give an early diagnosis of neurodegenerative disease and distinguish between Parkinsons and Alzheimers disease could be launched this summer, reports Marina Murphy in SCIs Chemistry & Industry magazine.

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Alzheimer’s vaccine clears plaque but has little effect on learning and memory impairment

UCI study suggests that combination of therapies provides best opportunity for Alzheimers treatment

A promising vaccine being tested for Alzheimers disease does what it is designed to do clear beta-amyloid plaques from the brain but it does not seem to help restore lost learning and memory abilities, according to a University of California, Irvine study.

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