Mouse model mimics clinical features

Neuroscientists at Johns Hopkins have discovered that mice lacking an enzyme that contributes to Alzheimer disease exhibit a number of schizophrenia-like behaviors. The finding raises the possibility that this enzyme may participate in the development of schiz…

The field of schizophrenia research has come alive with many exciting new potential approaches to treatment. From the introduction of chlorpromazine to the current day, all treatments approved by the U.S. Food and Drug Administration have had, at their core, a single treatment mechanism, the blockad…

Schizophrenia is one of the most debilitating of the major psychiatric disorders, and is also one of the most difficult to treat. Although numerous antipsychotic treatments are available, they can cause significant side effects and many patients experience only a partial relief of their symptoms and…

Findings provide clues for why people with schizophrenia have lower rates of cancer

A series of studies presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting elucidates evidence that there is a genetic link between schizophrenia and cancer, providing a surprisin…

Philadelphia, PA, September 26, 2007 – Do gene variants that convey risk for schizophrenia affect apparently healthy individuals” Although these genes are present in every human, individuals may have different versions of these genes, called alleles. While many people who possess these “risk all…

A new study reports important evidence for a potential new treatment approach for those diagnosed with schizophrenia. Schizophrenia is considered one of the most devastating of the major psychiatric disorders, which has three distinct facets, often referred to as “positive” (hallucinations, delu…

DISC1 makes protein that helps new neurons integrate into our neural network

How the gene that has been pegged as a major risk factor for schizophrenia and other mood disorders that affect millions of Americans contributes to these diseases remains unclear. However, the results of a new study by …

Several genes with strong associations to schizophrenia have evolved rapidly due to selection during human evolution, according to new research in the Proceedings of the Royal Society B (Wednesday 5 September 2007).

Researchers found a higher prevalence of the influence of so-called positive sel…